Vicena ✓

Vicena is an AI research agent that assists with scientific workflows across literature search, experimental design, lab simulation, and computational chemistry.

It reasons through research questions, selects the appropriate tools from a catalog of 24, executes them, and iterates until it produces cited results.For research and discovery, Vicena searches PubMed, arXiv, Google Scholar, and Google Patents in parallel, refining queries adaptively until coverage is comprehensive.

Every output links back to original sources with DOIs, authors, and publication dates. It also extracts step-by-step experimental protocols from papers, cross-referencing variables across sources and assigning confidence scores based on agreement.For lab simulation and validation, Vicena audits synthesis protocols for safety, yield feasibility, and reagent compatibility before the bench.

It checks protocols against physical constraints including thermodynamics, kinetics, vapor pressure, and GHS hazards, using curated rules and open libraries like RDKit, PubChem, Thermo, and ChemPy.

Outputs cite their sources and explicitly report coverage gaps rather than implying safety where data is unavailable.For computational chemistry, Vicena provides a full toolkit for reaction prediction (including Suzuki, Buchwald, Heck couplings via the Molecular Transformer neural network), retrosynthesis, molecular descriptors with Lipinski analysis, structural similarity via Morgan fingerprints, spectroscopy prediction (IR, NMR, MS), and quantum chemistry calculations (DFT, Hartree-Fock, MP2) built on PySCF and ASE.Vicena also includes a persistent Science Computer with a JupyterLab environment and over 30 scientific Python packages pre-installed.

The AI writes and executes code in real notebooks, debugging and iterating as it works. Files persist across sessions.The platform is built on 26 open scientific libraries, databases, and models including RDKit, PubChem, PySCF, the Molecular Transformer, SMARTS, and the Arrhenius equation.

Every numerical result traces back to the specific library that produced it.