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Verdict

A quick read before you dig into the full page.

Best if
You are biologists and need: Engineering antibodies with desired binding affinity and developability
Pick this when
AI-powered protein engineering platform for faster protein design and optimization

Overview

Cradle is an AI-powered protein engineering platform that helps biologists design improved proteins faster. It leverages powerful prediction algorithms and AI design suggestions to accelerate protein optimization for various applications, including therapeutics, agricultural solutions, and food ingredients. Cradle enables teams to generate protein candidates, track round status, explore reports, and co-optimize multiple properties like activity, binding, and stability.

Cradle screenshot

Best for

Short scenarios where Cradle tends to shine.

  • Engineering antibodies with desired binding affinity and developability

    Best for Biologists

  • Accelerating catalytic conversions for enzymes

    Best for Protein engineers

  • Improving the stability and efficacy of peptides

    Best for Researchers

  • Stabilizing antigens for vaccine development

    Best for Scientific teams

  • Developing proteins for therapeutics, agriculture, and food ingredients

    Best for Therapeutics developers

Example outputs 1

Sample generations and before/after results for Cradle.

Cradle screenshot
Cradle screenshot

Access & connections

Where you can use Cradle.

Platforms

Web

Capabilities

What this tool accepts, produces, and is strongest at.

Highlights

  • AI-driven protein design and optimization
  • Multi-property co-optimization
  • Data-driven model learning
  • Candidate generation and tracking
  • Reporting and analysis
  • Secure and private data management

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FAQ 5

What is Cradle?
Cradle is an AI-powered protein engineering platform that helps biologists design improved proteins faster. It leverages powerful prediction algorithms and AI design suggestions to accelerate protein optimization for various applications, including therapeutics, agricultural solutions, and food ingredients. Cradle enables teams to generate protein candidates, track round status, explore reports, and co-optimize multiple properties like activity, binding, and stability.
How to use Cradle?
To use Cradle, users import experimental data, define goals and assays, generate protein candidates using AI-driven design strategies, review predictive performance scores, and send sequences to the lab for validation. The platform tracks lab progress and learns from new assay data to improve model performance.
What types of proteins can Cradle work with?
Cradle is built for any protein and all properties. If you can measure it, you can optimize it with Cradle.
How does Cradle ensure data privacy and security?
With Cradle, your sequences and data remain private, secure, and entirely yours. Only you and those you invite can access your data, which is never used to train models for others. Protected by bank-grade security, your data stays secure at all times. Plus, you retain full ownership of your intellectual property.
Is Cradle a CRO?
Cradle isn’t a CRO, but they run their own wet lab in Amsterdam to ensure reliable and high-performing models from day one, while your proprietary data remains completely private.
Cradle
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